2001, Volume 4, Number 1, pp.58-63
The proposed dynamic model of conformational mobility in DNA
macromolecules is a generalization of the models used to study
conformational vibrations and conformational transition dynamics, as a
longitudinal component in this model is taken additionally into account.
For quantitative estimation of the obtained results (for the calculation
of a force constant) we used the DNA macromolecule elastic model in the
form of two twisted springs inserted into each other. As a result the
analysis, the dispersion curves for the generalized model of DNA
macromolecules have been obtained. Thus, the offered model of the
double-stranded DNA conformational mobility describes an experiment and
can be used for non-contradictory interpretation of the experimental data
and description of the DNA conformational dynamics in low-frequency
range.
Key words: conformational vibrations, force constants, dispersion
curves
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