2002, Vol.5, No.4, pp.462-469
The cardiac and respiratory systems each function in an
oscillatory manner, providing a nice example of coupled biological
oscillators. The modulation of the cardiac frequency, called
respiratory arrhythmia, has long been known. Synchronization
analyses have recently confirmed that, in a conscious healthy
subject at rest, the two systems can synchronize for a short
episodes of time. In experiments with paced respiration we show
that the synchronization and modulation can coexist. The
respiratory system is the driving system at all respiration
frequencies, whether paced or spontaneous.
Key words: biological oscillators, synchronization, modulation,
direction of coupling, cardiovascular system
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